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Prolotherapy is a nonsurgical treatment which stimulates healing of the underlying cause of joint pain and instability. Prolotherapy is also known as regenerative injection therapy. Prolotherapy is a nonsurgical treatment which stimulates healing of the underlying cause of joint pain and instability. Also known as regenerative injection therapy or nonsurgical ligament and tendon reconstruction it works by stimulating the body’s own natural healing processes and may repair injured ligaments and tendons to lay down new, strong collagen fibers and cells. The previously damaged tissue goes through the same healing cascade as when first injured and now prompts healing in the ligaments, tendons, and cartilage. It is 80% or more effective in curing pain caused by damaged, unhealed connective-tissue and returning the structure to full load bearing capacity. Prolotherapy is used to treat chronic pain in joints due to unhealed connective-tissue/ligament and tendon damage. Prolotherapy is used to treat cartilage loss in joints, particularly in hip joints and knee joints that cause pain with movement. Prolotherapy is used in the treatment of acute injuries especially sports injuries, when you want accelerated healing. Elite athletes are knowledgeable about prolotherapy and prefer this type of treatment. Prolotherapy is used to treat arthritis, back pain, neck pain, fibromyalgia, sports injuries, unresolved whiplash injuries, chronic tendinitis, partially torn tendons, ligaments, cartilage, degenerated or herniated disks, TMJ, and sciatica. This treatment is based on the theory that chronic pain is often caused by laxity or looseness of the ligaments that are responsible for keeping a joint stable. When ligaments and tendons are loose, the body compensates by using muscles to stabilize the joint thus resulting in muscle spasm and pain. A lack of ligament and tendon healing leads to chronic pain. Prolotherapy treatment involves a series of injections of natural solutions into the injured area around such ligaments and tendons. These solutions caused the tissue to proliferate or grow, increasing the strength and thickness of the ligaments and tendons. This tightens the joint and relieves the burden on the surrounding muscles thus stopping muscle spasms and the associated pain. Ligaments, which are the structural “bands” that hold bones to bones can become weak and lose their original strength or endurance. The blood supply to ligaments and tendons is limited and therefore healing is slow or incomplete, and the ligaments have many nerve endings that are responsible for causing the pain in the injured area. Tendons, which connect muscles to bones, become weak and painful when injured due to nonhealing